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Article

Strong correlation between molecular changes in endometrial carcinomas and concomitant hyperplasia.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jun 2015

Zauber Peter, Denehy Thad R, Taylor Robert R, Ongcapin Emelie H, Marotta Stephen, Sabbath-Solitare Marlene

Abstract excerpt

OBJECTIVE: Endometrial cancer (EC) results from the accumulation of numerous genetic abnormalities contributing to the progression from hyperplasia to EC. Information on these various genetic changes has been primarily derived from studying groups of either hyperplasias or cancers.We evaluated both hyperplastic and EC tissue obtained from the same surgical specimens for KRAS mutations, microsatellite instability...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endometrial Hyperplasia

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Share to Proto-Oncogene Proteins p21(ras)

Source

Identifiers

PMID: 25768080
DOI: 10.1097/IGC.0000000000000421

Genes

KRAS

Provenance

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