Article
K-ras mutations in endometrial carcinomas with microsatellite instability.
The Journal of pathology - 1 Feb 2001
Lagarda H, Catasus L, Arguelles R, Matias-Guiu X, Prat J
Abstract excerpt
K-ras mutations are known to occur in hyperplasias and carcinomas of the endometrium. No clear correlation has been found yet between K-ras mutations and microsatellite instability (MI) in these lesions. Fifty-eight endometrial carcinomas (ECs) and 22 endometrial hyperplasias (EHs) were analysed for K-ras mutation by single-strand conformational polymorphism analysis (SSCP), restriction analysis, and DNA...
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