Microsatellite instability and somatic mutations in endometrial carcinomas.

doi:10.1006/gyno.1998.5154

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Article

Microsatellite instability and somatic mutations in endometrial carcinomas.

Gynecologic oncology - 1 Oct 1998

Sakamoto T, Murase T, Urushibata H, Kato K, Takada H, Imamura T, Mori H, Wake N

Abstract excerpt

Recently, microsatellite instability (MI) has been demonstrated in some types of human cancers. In this study, we attempted to determine the frequency of MI in endometrial cancers and evaluate whether replication error (RER)-positive phenotype is correlated with known genetic mutations or the abe...

Topics

Chromosomes, Human, Pair 18
DNA Replication
Endometrial Neoplasms
Female
Genes, p53
Genes, ras
Humans
Loss of Heterozygosity
Microsatellite Repeats
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational

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