Article
Microsatellite instability and somatic mutations in endometrial carcinomas.
Gynecologic oncology - 1 Oct 1998
Sakamoto T, Murase T, Urushibata H, Kato K, Takada H, Imamura T, Mori H, Wake N
Abstract excerpt
Recently, microsatellite instability (MI) has been demonstrated in some types of human cancers. In this study, we attempted to determine the frequency of MI in endometrial cancers and evaluate whether replication error (RER)-positive phenotype is correlated with known genetic mutations or the aberrations of other pathways in endometrial cancers. Seventy-two primary endometrial cancers were examined for...
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