Article
Analysis of potential cancer biomarkers in mitochondrial DNA.
Current opinion in molecular therapeutics - 1 Dec 2006
Jakupciak John P, Dakubo Gabriel D, Maragh Samantha, Parr Ryan L
Abstract excerpt
Understanding mitochondrial biology is a fundamental research goal in human genetics and medicine. The use of mitochondria to serve as a biomarker is rapidly expanding in disciplines ranging from cancer, rare metabolic diseases, aging, the tracing of human migration patterns in antiquity, population characterization using maternal markers, and human identification. Mitochondrial DNA (mtDNA) mutations occur...
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