Article
Potential pitfalls in MitoChip detected tumor-specific somatic mutations: a call for caution when interpreting patient data.
BMC cancer - 30 Oct 2010
Palanichamy Malliya Gounder, Zhang Ya-Ping
Abstract excerpt
BACKGROUND: Several investigators have employed high throughput mitochondrial sequencing array (MitoChip) in clinical studies to search mtDNA for markers linked to cancers. In consequence, a host of somatic mtDNA mutations have been identified as linked to different types of cancers. However, clo...
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