Article
The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.
Genome research - 1 May 2004
Maitra Anirban, Cohen Yoram, Gillespie Susannah E D, Mambo Elizabeth, Fukushima Noriyoshi, Hoque Mohammad O, Shah Nila, Goggins Michael, Califano Joseph, Sidransky David, Chakravarti Aravinda
Abstract excerpt
Somatic mitochondrial mutations are common in human cancers, and can be used as a tool for early detection of cancer. We have developed a mitochondrial Custom Reseq microarray as an array-based sequencing platform for rapid and high-throughput analysis of mitochondrial DNA. The MitoChip contains oligonucleotide probes synthesized using standard photolithography and solid-phase synthesis, and is able to sequence...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
