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Article

Genetic analysis reveals essential and non-essential amino acids within the telomeric DNA-binding interface of Cdc13p.

The Biochemical journal - 15 Apr 2007

Lin Yi-Chien, Wu Lee Yan-Hwa, Lin Jing-Jer

Abstract excerpt

Cdc13p is a specific single-stranded telomeric DNA-binding protein of Saccharomyces cerevisiae. It is involved in protecting telomeres and regulating telomere length. The telomere-binding domain of Cdc13p is located between residues 497 and 693, and its structure has been resolved by NMR spectroscopy. A series of aromatic, hydrophobic and basic residues located at the DNA-binding surface of Cdc13p are involved in...

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Identifiers

PMID: 17166094
DOI: 10.1042/BJ20061698
PMCID: PMC1874236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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