Article
New function of CDC13 in positive telomere length regulation.
Molecular and cellular biology - 1 Jul 2001
Meier B, Driller L, Jaklin S, Feldmann H M
Abstract excerpt
Two roles for the Saccharomyces cerevisiae Cdc13 protein at the telomere have previously been characterized: it recruits telomerase to the telomere and protects chromosome ends from degradation. In a synthetic lethality screen with YKU70, the 70-kDa subunit of the telomere-associated Yku heterodimer, we identified a new mutation in CDC13, cdc13-4, that points toward an additional regulatory function of CDC13....
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