Optimal haplotype block-free selection of tagging SNPs for genome-wide association studies.

doi:10.1101/gr.2570004

Article

Optimal haplotype block-free selection of tagging SNPs for genome-wide association studies.

Genome research - 1 Aug 2004

Halldórsson Bjarni V, Bafna Vineet, Lippert Ross, Schwartz Russell, De La Vega Francisco M, Clark Andrew G, Istrail Sorin

Abstract excerpt

It is widely hoped that the study of sequence variation in the human genome will provide a means of elucidating the genetic component of complex diseases and variable drug responses. A major stumbling block to the successful design and execution of genome-wide disease association studies using si...

Topics

Algorithms
Chromosomes, Human, Pair 22
Genetic Variation
Haplotypes
Humans
Linkage Disequilibrium
Models, Genetic
Polymorphism, Single Nucleotide
Research Design

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