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Article

Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling.

Biochemical and biophysical research communications - 26 Jan 2007

Taniguchi Koji, Ayada Toranoshin, Ichiyama Kenji, Kohno Ri-Ichiro, Yonemitsu Yoshikazu, Minami Yasuhiro, Kikuchi Akira, Maehara Yoshihiko, Yoshimura Akihiko

Abstract excerpt

Sprouty genes encode cytoplasmic membrane-associated proteins that inhibit receptor tyrosine kinase signaling. Four orthologs of Drosophila Sprouty (dSpry) (Sprouty1-4) have been identified in mammals. Physiological function of Sprouty1 and Sprouty2 has been investigated using gene targeting approaches, however to date detailed examination of Sprouty4 knockout (KO) mice has not been reported. In this study,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17156747
DOI: 10.1016/j.bbrc.2006.11.107

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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