Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila.

doi:10.1242/dev.126.11.2515

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Article

Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila.

Development (Cambridge, England) - 1 Jun 1999

Kramer S, Okabe M, Hacohen N, Krasnow M A, Hiromi Y

Abstract excerpt

Extracellular factors such as FGF and EGF control various aspects of morphogenesis, patterning and cellular proliferation in both invertebrates and vertebrates. In most systems, it is primarily the distribution of these factors that controls the differential behavior of the responding cells. Here we describe the role of Sprouty in eye development. Sprouty is an extracellular protein that has been shown to...

Topics

Animals
Drosophila
Drosophila Proteins
ErbB Receptors
Ethyl Methanesulfonate
Eye
Eye Proteins
Fibroblast Growth Factors
Gene Expression Regulation, Developmental
Histocytochemistry
Insect Proteins
Membrane Proteins
Mutagenesis
Nerve Tissue Proteins
Nervous System
Phenotype
Receptor Protein-Tyrosine Kinases
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 10226010
DOI: 10.1242/dev.126.11.2515

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