Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo.

Developmental biology - 1 Oct 2011

Simrick Subreena, Lickert Heiko, Basson M Albert

Abstract excerpt

Fibroblast growth factor (FGF) signalling has important roles in the development of the embryonic pharyngeal (branchial) arches, but its effects on innervation of the arches and associated structures have not been studied extensively. We investigated the consequences of deleting two receptor tyrosine kinase (RTK) antagonists of the Sprouty (Spry) gene family on the early development of the branchial nerves. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Branchial Region
Share to Fibroblast Growth Factor 8
Share to Haploinsufficiency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to In Situ Hybridization

Share to Intracellular Signaling Peptides and Proteins

Share to Neural Crest

Share to Phosphoproteins

Share to Vagus Nerve

Source

Open in PubMed Open full text

Identifiers

PMID: 21806979
DOI: 10.1016/j.ydbio.2011.07.024
PMCID: PMC3368431

Genes

FGF8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sprouty genes are essential for the normal development of epibranchial ganglia in the mouse embryo.PMID 21806979Read ↗

Sprouty2 and Sprouty4 are essential for embryonic morphogenesis and regulation of FGF signaling.Semantic proximity Read ↗

Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila.Semantic proximity Read ↗

Specification of epibranchial placodes in zebrafish.Semantic proximity Read ↗

Notch signalling regulates epibranchial placode patterning and segregation.Semantic proximity Read ↗

Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1.Semantic proximity Read ↗

Nkx2.2 and Nkx2.9 are the key regulators to determine cell fate of branchial and visceral motor neurons in caudal hindbrain.Semantic proximity Read ↗

Chondrogenic and gliogenic subpopulations of neural crest play distinct roles during the assembly of epibranchial ganglia.Semantic proximity Read ↗

Spry1 and spry2 are essential for development of the temporomandibular joint.Semantic proximity Read ↗

Sprouty gain of function disrupts lens cellular processes and growth by restricting RTK signaling.Semantic proximity Read ↗

Induction of the epibranchial placodesSemantic proximity Read ↗

Coordinated activity of Spry1 and Spry2 is required for normal development of the external genitalia.Semantic proximity Read ↗

The genetic basis of mammalian neurulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.