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Article

Spry1 and spry2 are essential for development of the temporomandibular joint.

Journal of dental research - 1 Apr 2012

Purcell P, Jheon A, Vivero M P, Rahimi H, Joo A, Klein O D

Abstract excerpt

The temporomandibular joint (TMJ) is a specialized synovial joint essential for the function of the mammalian jaw. The main components of the TMJ are the mandibular condyle, the glenoid fossa of the temporal bone, and a fibrocartilagenous disc interposed between them. The genetic program for the development of the TMJ remains poorly understood. Here we show the crucial role of sprouty (Spry) genes in TMJ...

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Identifiers

PMID: 22328578
DOI: 10.1177/0022034512438401
PMCID: PMC3310757

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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