Article
Cytogenetic analysis of human bile for mutagenicity and co-mutagenicity.
The Tohoku journal of experimental medicine - 1 Apr 1991
Watanabe M, Takagi S, Magara J, Mano H, Tsunoda M, Nakadaira H, Endoh K, Yamamoto M, Kato K, Akai S
Abstract excerpt
Cytogenetic analysis was used to test whether or not human bile induced chromosome abnormalities in lymphocytes grown in culture. Bile was obtained from gallbladders resected for various reasons such as cholecystitis, cholelithiasis, polypus and cancers of the biliary tract, stomach and pancreas. After adding human bile to a final concentration of 25 microliters/ml or 12.5 microliters/ml, the culture medium was...
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