Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test.

BMC complementary and alternative medicine - 1 Jul 2014

Lee Mee-Young, Seo Chang-Seob, Kim Ji-Young, Shin Hyeun-Kyoo

Abstract excerpt

BACKGROUND: Guibi-Tang is a traditional herbal prescription made from 12 different herbs that is used in the treatment of amnesia and poor memory. METHODS: In the present study, we evaluated the acute oral toxicity and genotoxic potential of Guibi-Tang water extract (GBT) at doses up to 2000 μg/plate an using a bacterial reverse mutation test (Ames test) with Salmonella typhimurium strains TA100, TA1535, TA98,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteria
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cricetulus

Share to Drugs, Chinese Herbal

Share to Erythrocytes

Share to Mice, Inbred ICR

Share to Mutagenicity Tests

Share to Rats, Sprague-Dawley

Source

Open in PubMed Open full text

Identifiers

PMID: 24985139
DOI: 10.1186/1472-6882-14-215
PMCID: PMC4094639

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test.PMID 24985139Read ↗

In vitro and in vivo evaluation of the genotoxicity of Gumiganghwal-tang, a traditional herbal prescription.Semantic proximity Read ↗

Acute toxicity and genotoxicity study of fermented traditional herb formula Guibi-tang.Semantic proximity Read ↗

Genotoxicity induced by medicinal plantsSemantic proximity Read ↗

Evaluation of oral toxicity and genotoxicity of Achyranthis Radix extract.Semantic proximity Read ↗

Antimutagenic and anticancer activity of Darjeeling tea in multiple test systems.Semantic proximity Read ↗

Evaluation of a water extract of So-Cheong-Ryong-Tang for acute toxicity and genotoxicity using in vitro and in vivo tests.Semantic proximity Read ↗

Evaluation of the genotoxicity of extracts of Houttuynia cordata Thunb.Semantic proximity Read ↗

Genotoxicity guidelines recommended by International Conference of Harmonization (ICH).Semantic proximity Read ↗

Genotoxicity and subacute toxicity studies of a new astaxanthin-containing Phaffia rhodozyma extract.Semantic proximity Read ↗

Genotoxicity evaluation of the naturally-derived food colorant, gardenia blue, and its precursor, genipinSemantic proximity Read ↗

Genotoxicity Assessment of Hwanglyeonhaedok-Tang: An Herbal Formula Evaluated Using the In Vivo Alkaline Comet Assay and Pig-a Gene Mutation Assay in RatsSemantic proximity Read ↗

Genotoxicity test battery - An assessment of its utility in early drug development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.