Article
Genotoxicity of aloeemodin in vitro and in vivo.
Mutation research - 1 Mar 1996
Heidemann A, Völkner W, Mengs U
Abstract excerpt
The present in vitro and in vivo experiments were undertaken to clarify the genotoxic potential of the hydroxyanthrachinone aloeemodin which can be found in different plant derived products for therapy of constipation. The results demonstrate that aloeemodin is able to induce mutagenic effects in...
Topics
- Animals
- Bone Marrow
- Bone Marrow Cells
- CHO Cells
- Cathartics
- Cell Line
- Chromosome Aberrations
- Cricetinae
- DNA
- Emodin
- Female
- Liver
- Male
- Mice
- Mice, Inbred Strains
- Micronucleus Tests
- Mutagenicity Tests
- Mutagens