Article
The genotoxic effects of hepatitis B virus to host DNA.
Mutagenesis - 1 Mar 2005
Ozkal Pinar, Ilgin-Ruhi Hatice, Akdogan Meral, Elhan Atilla Halil, Kaçar Sabite, Sasmaz Nurgül
Abstract excerpt
Chronic viral hepatitis is the main cause of chronic liver disease, cirrhosis and hepatocellular carcinoma throughout the world. Hepatitis B virus (HBV) has mutagenic effects on somatic cells. HBV may be showing these mutagenic effects through its viral proteins or through integrating into host DNA. The aim of this study was to determine whether HBV has a genotoxic effect on host DNA or not. Peripheral blood...
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