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Article

Clastogenic effects induced in vitro by CCNU and AMD during G2-phase in bone marrow cells of Wistar rats.

Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2000

Georgian L

Abstract excerpt

Three concentrations of CCNU and AMD (1, 5 and 10 micrograms/ml) were given to bone marrow cells of Wistar rats immediately after their removal from the body into the culture medium. Abnormal metaphases observed 2, 3 and 4 h later were considered to represent the effect induced by the two drugs on G2-phase chromosomes in a cell population that traversed in vivo previous phases of the cell cycle. In order to...

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PMID: 1814514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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