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Article

Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population.

International archives of allergy and immunology - 1 Jan 2012

Kumar Amrendra, Sharma Shilpy, Agrawal Anurag, Ghosh Balaram

Abstract excerpt

BACKGROUND: Atopic asthma, the most common chronic disease affecting children and young adults, is a complex disorder with variable phenotypes. Cysteine leukotrienes (Cys-LTs) are powerful bronchoconstrictors and play a critical role in airway inflammation and remodeling that are characteristic of asthma. OBJECTIVE: To investigate the association of ALOX5, LTC4S and CysLTR2 gene polymorphisms with atopic asthma...

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Identifiers

PMID: 22722751
DOI: 10.1159/000336675

Genes

ALOX5

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