Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes.

BMC immunology - 15 Dec 2009

Sokolowska Milena, Wodz-Naskiewicz Karolina, Cieslak Malgorzata, Seta Karolina, Bednarek Andrzej K, Pawliczak Rafal

Abstract excerpt

BACKGROUND: Cysteinyl leukotrienes are potent inflammatory mediators implicated in the pathogenesis of asthma. Human cysteinyl leukotriene receptor 1 (CYSLTR1) gene contains five exons that are variably spliced. Within its promoter few polymorphisms were described. To date, there has been no evidence about the expression of different splice variants of CysLT1 in asthma and their association with CYSLTR1 promoter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alternative Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asthma

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 20003473
DOI: 10.1186/1471-2172-10-63
PMCID: PMC2805608

Genes

CYSLTR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variable expression of cysteinyl leukotriene type I receptor splice variants in asthmatic females with different promoter haplotypes.PMID 20003473Read ↗

Functional polymorphism and differential regulation of CYSLTR1 transcription in human airway smooth muscle and monocytes.Semantic proximity Read ↗

Cysteinyl leukotriene receptor 1 promoter polymorphism is associated with aspirin-intolerant asthma in males.Semantic proximity Read ↗

Functional Characterization of Human Cysteinyl Leukotriene 1 Receptor Gene StructureSemantic proximity Read ↗

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association StudiesSemantic proximity Read ↗

G-protein-coupled receptors and asthma endophenotypes: the cysteinyl leukotriene system in perspective.Semantic proximity Read ↗

Cysteinyl leukotriene receptor 1 gene variation and risk of asthma.Semantic proximity Read ↗

927T>C polymorphism of the cysteinyl-leukotriene type-1 receptor (CYSLTR1) gene in children with asthma and atopic dermatitis.Semantic proximity Read ↗

Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma.Semantic proximity Read ↗

Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization.Semantic proximity Read ↗

Association between a polymorphism in cysteinyl leukotriene receptor 2 on chromosome 13q14 and atopic asthma.Semantic proximity Read ↗

Association of the -1072G/A polymorphism in the LTC4S gene with asthma in an Indian population.Semantic proximity Read ↗

ALOX5 polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.