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Article

Zfp423 controls proliferation and differentiation of neural precursors in cerebellar vermis formation.

Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 2006

Alcaraz Wendy A, Gold David A, Raponi Eric, Gent Peter M, Concepcion Dorothy, Hamilton Bruce A

Abstract excerpt

Neural stem cells and progenitors in the developing brain must choose between proliferation with renewal and differentiation. Defects in navigating this choice can result in malformations or cancers, but the genetic mechanisms that shape this choice are not fully understood. We show by positional cloning that the 30-zinc finger transcription factor Zfp423 (OAZ) is required for patterning the development of...

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Identifiers

PMID: 17151198
DOI: 10.1073/pnas.0609184103
PMCID: PMC1748242

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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