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Transcriptional Regulator ZEB2 Is Essential for Bergmann Glia Development

11 Jan 2018

Abstract excerpt

Bergmann glia facilitate granule neuron migration during development and maintain the cerebellar organization and functional integrity. At present, molecular control of Bergmann glia specification from cerebellar radial glia is not fully understood. In this report, we show that ZEB2 (aka, SIP1 or ZFHX1B), a Mowat–Wilson syndrome-associated transcriptional regulator, is highly expressed in Bergmann glia, but...

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PMID: 29326173
DOI: 10.1523/jneurosci.2674-17.2018

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