Article

Integrated single-cell transcriptomic and epigenetic analyses of cell-state transition and lineage commitment in the embryonic mouse cerebellum

2021-08-08

Abstract excerpt

<h4>ABSTRACT</h4> Recent studies using single-cell RNA-seq have revealed cellular heterogeneity in the developing mammalian cerebellum, yet the regulatory logic underlying this cellular diversity remains to be elucidated. Using integrated single-cell RNA and ATAC analyses, we resolved developmental trajectories of cerebellar progenitors and identified putative trans - and cis - elements that control cell state...

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Literature Corpus work: 73d44bab-a5e9-5e6d-afd4-1262dcd8089c
DOI: 10.1101/2021.08.08.455565

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