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Article

Polymorphism in the IL-1alpha (-889) locus associated with elevated risk of primary open angle glaucoma.

Molecular vision - 15 Nov 2006

Wang Chun-Yuan, Shen Ying-Cheng, Lo Fai-Yun, Su Chien-Hui, Lee Shi-Huang, Lin Keng-Hung, Tsai Hin-Yeung, Kuo Ni-Wen, Fan Seng-Sheen

Abstract excerpt

PURPOSE: Recent laboratory evidence indicates that the inflammatory cytokine, interleukin-1 (IL-1), has either protective or adverse effects on primary open angle glaucoma (POAG). Inheritance of the IL-1alpha (-889) polymorphism (the T allele), previously shown to increase IL-1 production, has been associated with an elevated risk of Alzheimer's disease. The neuronal injuries associated with Alzheimer's disease...

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PMID: 17149369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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