Article
Normal tension glaucoma is not associated with the interleukin -1alpha (-889) genetic polymorphism.
Journal of glaucoma - 1 Mar 2007
Wang Chun-Yuan, Shen Ying-Cheng, Lo Fai-Yun, Su Chien-Hui, Lee Shi-Huang, Tsai Hin-Yeung, Fan Seng-Sheen
Abstract excerpt
BACKGROUND: Factors other than intraocular pressure are likely to play a role in the pathogenesis of glaucomatous optic neuropathy, particularly in individuals with normal tension glaucoma (NTG). Recent laboratory evidence has shown that there are potential similarities between Alzheimer disease and NTG in cellular apoptosis leading to neurodegeneration. IL-1alpha (-889) T allele polymorphism has been found to...
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