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Article

Neurodegenerative Genes Polymorphisms of the -491A/T APOE, the -877T/C APP and the Risk of Primary Open-angle Glaucoma in the Polish Population.

Ophthalmic genetics - 1 Jun 2015

Nowak Alicja, Przybylowska-Sygut Karolina, Gacek Mira, Kaminska Anna, Szaflik Jacek P, Szaflik Jerzy, Majsterek Ireneusz

Abstract excerpt

BACKGROUND: Glaucoma is characterized by optic neuropathy of the retinal ganglion cell. It may be possible that β-amyloid (Aβ) and apolipoprotein E (APOE), the main proteins of the pathogenesis of AD, play a role in glaucoma development. The aim of this study was to evaluate a relationship between the APP and APOE gene polymorphisms and the risk of primary open-angle glaucoma (POAG) occurrence. MATERIALS AND...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24073598
DOI: 10.3109/13816810.2013.838277

Genes

APOE
APP

Provenance

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