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Article

Association of IL1A and IL1B loci with primary open angle glaucoma.

BMC medical genetics - 19 Jun 2010

Mookherjee Suddhasil, Banerjee Deblina, Chakraborty Subhadip, Banerjee Antara, Mukhopadhyay Indranil, Sen Abhijit, Ray Kunal

Abstract excerpt

BACKGROUND: Recent studies suggest that glaucoma is a neurodegenerative disease in which secondary degenerative losses occur after primary insult by raised Intraocular pressure (IOP) or by other associated factors. It has been reported that polymorphisms in the IL1A and IL1B genes are associated with Primary Open Angle Glaucoma (POAG). The purpose of our study was to investigate the role of these polymorphisms in...

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Glaucoma, Open-Angle
Haplotypes
India
Interleukin-1alpha
Interleukin-1beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Intraocular Pressure

Linkage Disequilibrium

Multigene Family

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Identifiers

PMID: 20565898
DOI: 10.1186/1471-2350-11-99
PMCID: PMC2909939

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