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Article

Association of tumour necrosis factor-alpha -308 G/A polymorphism with primary open-angle glaucoma.

Clinical & experimental ophthalmology - 1 Jan 2000

Bozkurt Banu, Mesci Lutfiye, Irkec Murat, Ozdag Burcin B, Sanal Ozden, Arslan Umut, Ersoy Fugen, Tezcan Ilhan

Abstract excerpt

BACKGROUND: Tumour necrosis factor-alpha (TNF-α) is an important proinflammatory cytokine driving axonal degeneration and retinal ganglion cell apoptosis in glaucoma. The aim of the study was to evaluate the association of TNF-α -308 G/A and -238 G/A polymorphisms with primary open-angle glaucoma (POAG). DESIGN: A prospective, case-control study, university hospital setting. PARTICIPANTS: Eighty-six POAG patients...

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Source

Identifiers

PMID: 21575121
DOI: 10.1111/j.1442-9071.2011.02595.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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