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Article

Gene polymorphisms of the MMP1, MMP9, MMP12, IL-1β and TIMP1 and the risk of primary open-angle glaucoma.

Acta ophthalmologica - 1 Nov 2013

Markiewicz Lukasz, Majsterek Ireneusz, Przybylowska Karolina, Dziki Lukasz, Waszczyk Maja, Gacek Mira, Kaminska Anna, Szaflik Jerzy, Szaflik Jacek P

Abstract excerpt

BACKGROUND: Primary open-angle glaucoma (POAG) is the main cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their regulators (TIMPs and ILs) have been extensively studied as POAG risk factors. Recent reports have showed several single-nucleotide polymorphisms (SNPs) for MMPs, TIMPs and ILs encoding genes in patients with POAG. The aim of this study was to investigate association of...

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Source

Identifiers

PMID: 23800300
DOI: 10.1111/aos.12149

Genes

MMP9
MMP1
TIMP1
MMP12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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