Article
Ethanol sensitivity: a central role for CREB transcription regulation in the cerebellum.
BMC genomics - 5 Dec 2006
Acquaah-Mensah George K, Misra Vikas, Biswal Shyam
Abstract excerpt
BACKGROUND: Lowered sensitivity to the effects of ethanol increases the risk of developing alcoholism. Inbred mouse strains have been useful for the study of the genetic basis of various drug addiction-related phenotypes. Inbred Long-Sleep (ILS) and Inbred Short-Sleep (ISS) mice differentially express a number of genes thought to be implicated in sensitivity to the effects of ethanol. Concomitantly, there is...
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