Article
Exome sequencing and arrayCGH detection of gene sequence and copy number variation between ILS and ISS mouse strains.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2014
Dumas Laura, Dickens C Michael, Anderson Nathan, Davis Jonathan, Bennett Beth, Radcliffe Richard A, Sikela James M
Abstract excerpt
It has been well documented that genetic factors can influence predisposition to develop alcoholism. While the underlying genomic changes may be of several types, two of the most common and disease associated are copy number variations (CNVs) and sequence alterations of protein coding regions. The goal of this study was to identify CNVs and single-nucleotide polymorphisms that occur in gene coding regions that...
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