Article
The genomic determinants of alcohol preference in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 May 2008
Tabakoff Boris, Saba Laura, Kechris Katherina, Hu Wei, Bhave Sanjiv V, Finn Deborah A, Grahame Nicholas J, Hoffman Paula L
Abstract excerpt
Searches for the identity of genes that influence the levels of alcohol consumption by humans and other animals have often been driven by presupposition of the importance of particular gene products in determining positively or negatively reinforcing effects of ethanol. We have taken an unbiased approach and performed a meta-analysis across three types of mouse populations to correlate brain gene expression with...
Topics
- Alcohol Drinking
- Animals
- Brain
- Chromosome Mapping
- Food Preferences
- Gene Expression Profiling
- Male
- Meta-Analysis as Topic
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Inbred Strains
- Oligonucleotide Array Sequence Analysis