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Article

Inhibition of myogenesis by the H-ras oncogene: implication of a role for protein kinase C.

The Journal of cell biology - 1 Aug 1991

Vaidya T B, Weyman C M, Teegarden D, Ashendel C L, Taparowsky E J

Abstract excerpt

Expression of the oncogenic form of H-ras p21 in the mouse myogenic cell line, 23A2, blocks myogenesis and inhibits expression of the myogenic regulatory factor gene, MyoD1. Previous studies from a number of laboratories have demonstrated that the activation of ras p21 is associated with changes in phospholipid metabolism that directly, or indirectly, lead to elevated levels of intracellular diacylglycerol and...

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Identifiers

PMID: 1714463
DOI: 10.1083/jcb.114.4.809
PMCID: PMC2289900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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