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Article

Differentiation of vascular smooth muscle cells and the regulation of protein kinase C-alpha.

Circulation research - 1 Jan 1995

Haller H, Lindschau C, Quass P, Distler A, Luft F C

Abstract excerpt

Dedifferentiation and proliferation of vascular smooth muscle cells (VSMCs) are important features of atherosclerosis. The molecular mechanisms are largely unclear; however, protein kinase C (PKC) is a key enzyme in the intracellular signaling pathways that mediate this process. We studied the activity and immunoreactivity of PKC-alpha in primary cultures of VSMCs from rat aortas under different conditions of...

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PMID: 8001276
DOI: 10.1161/01.res.76.1.21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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