Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Up-regulation of nuclear PLCbeta1 in myogenic differentiation.

Journal of cellular physiology - 1 Jun 2003

Faenza Irene, Bavelloni Alberto, Fiume Roberta, Lattanzi Giovanna, Maraldi Nadir M, Gilmour R Stewart, Martelli Alberto M, Suh Pann-Ghill, Billi Anna Maria, Cocco Lucio

Abstract excerpt

Phospholipase C beta(1) (PLCbeta(1)) signaling in both cell proliferation and differentiation has been largely investigated, but its role in myoblast differentiation is still unclear. The C2C12 myogenic cell line has been used in this study in order to find out the role of the two subtypes of PLCbeta(1), i.e., a and b in this process. C2C12 myoblast proliferate in response to mitogens and upon mitogen withdrawal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to Enzyme Activation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Isoenzymes

Share to Muscle, Skeletal

Share to Nuclear Localization Signals

Share to Phospholipase C beta

Share to Type C Phospholipases

Share to Up-Regulation

Source

Identifiers

PMID: 12704654
DOI: 10.1002/jcp.10264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Up-regulation of nuclear PLCbeta1 in myogenic differentiation.PMID 12704654Read ↗

Catalytic activity of nuclear PLC-beta(1) is required for its signalling function during C2C12 differentiation.Semantic proximity Read ↗

Modulation of nuclear PI-PLCbeta1 during cell differentiationSemantic proximity Read ↗

A role for nuclear phospholipase Cbeta 1 in cell cycle control.Semantic proximity Read ↗

PKR is a novel functional direct player that coordinates skeletal muscle differentiation via p38MAPK/AKT pathways.Semantic proximity Read ↗

Stimulation of C2C12 myoblast growth by basic fibroblast growth factor and insulin-like growth factor 1 can occur via mitogen-activated protein kinase-dependent and -independent pathways.Semantic proximity Read ↗

Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts.Semantic proximity Read ↗

Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.Semantic proximity Read ↗

Rap1A protein interferes with various MAP kinase activating pathways in skeletal myogenic cells.Semantic proximity Read ↗

Differentiation of C2C12 myoblasts expressing lamin A mutated at a site responsible for Emery-Dreifuss muscular dystrophy is improved by inhibition of the MEK-ERK pathway and stimulation of the PI3-kinase pathway.Semantic proximity Read ↗

The role of insulin-like-growth factor binding protein 2 (IGFBP2) and phosphatase and tensin homologue (PTEN) in the regulation of myoblast differentiation and hypertrophy.Semantic proximity Read ↗

Activation of Akt is essential for the propagation of mitochondrial respiratory stress signaling and activation of the transcriptional coactivator heterogeneous ribonucleoprotein A2.Semantic proximity Read ↗

Regulation of insulin-like growth factor-dependent myoblast differentiation by Foxo forkhead transcription factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.