Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells.

doi:10.1074/jbc.270.47.28183

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Article

Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells.

The Journal of biological chemistry - 24 Nov 1995

Teboul L, Gaillard D, Staccini L, Inadera H, Amri E Z, Grimaldi P A

Abstract excerpt

Fatty acids and thiazolidinediones act as potent activators of the adipose differentiation program in established preadipose cell lines. In this report, the effects of these agents on the differentiation pathway of myoblasts have been investigated. Exposure of C2C12N myoblasts (a subclone of the C2C12 cell line) to thiazolidinediones or fatty acids prevents the expression of myogenin, alpha-actin, and creatine...

Topics

5,8,11,14-Eicosatetraynoic Acid
Actins
Adipose Tissue
Animals
Biomarkers
Carrier Proteins
Cell Differentiation
Cell Division
Chromans
Clone Cells
Creatine Kinase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Fatty Acid-Binding Protein 7

Fatty Acid-Binding Proteins

Fatty Acids, Nonesterified

Gene Expression

Glycerolphosphate Dehydrogenase

Hypoglycemic Agents

Linoleic Acid

Source

Open in PubMed

Identifiers

PMID: 7499310
DOI: 10.1074/jbc.270.47.28183

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7499310-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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