Article
Ethnic variation in CYP2A6 and association of genetically slow nicotine metabolism and smoking in adult Caucasians.
Pharmacogenetics - 1 Sept 2004
Schoedel Kerri A, Hoffmann Ewa B, Rao Yushu, Sellers Edward M, Tyndale Rachel F
Abstract excerpt
Genetically variable CYP2A6 is the primary enzyme that inactivates nicotine to cotinine. Our objective was to investigate allele frequencies among five ethnic groups and to investigate the relationship between genetically slow nicotine metabolic inactivation and smoking status, cigarette consumpt...
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