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Article

Genetically decreased CYP2A6 and the risk of tobacco dependence: a prospective study of novice smokers.

Tobacco control - 1 Dec 2004

O'Loughlin J, Paradis G, Kim W, DiFranza J, Meshefedjian G, McMillan-Davey E, Wong S, Hanley J, Tyndale R F

Abstract excerpt

OBJECTIVE: Case control studies in adults suggest that defective alleles in the gene that codes for the hepatic cytochrome P450 2A6 (CYP2A6) protect against nicotine dependence (ND) and higher levels of cigarette consumption. These two hypotheses were tested in young adolescents. DESIGN: Self rep...

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Source

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Identifiers

PMID: 15564629
DOI: 10.1136/tc.2003.007070
PMCID: PMC1747926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15564629-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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