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Article

Cardiac dysfunction in the R6/2 mouse model of Huntington's disease.

Neurobiology of disease - 1 Feb 2007

Mihm Michael J, Amann Deborah M, Schanbacher Brandon L, Altschuld Ruth A, Bauer John Anthony, Hoyt Kari R

Abstract excerpt

Recent evidence suggests that mutant huntingtin protein-induced energetic perturbations contribute to neuronal dysfunction in Huntington's disease (HD). Given the ubiquitous expression of huntingtin, other cell types with high energetic burden may be at risk for HD-related dysfunction. Early-onse...

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Identifiers

PMID: 17126554
DOI: 10.1016/j.nbd.2006.09.016
PMCID: PMC1850107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17126554-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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