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Article

Examining Cardiomyocyte Dysfunction Using Acute Chemical Induction of an Ageing Phenotype.

International journal of molecular sciences - 27 Dec 2019

Masoud Said, McDonald Fraser, Bister Dirk, Kotecki Claire, Bootman Martin D, Rietdorf Katja

Abstract excerpt

Much effort is focussed on understanding the structural and functional changes in the heart that underlie age-dependent deterioration of cardiac performance. Longitudinal studies, using aged animals, have pinpointed changes occurring to the contractile myocytes within the heart. However, whilst longitudinal studies are important, other experimental approaches are being advanced that can recapitulate the...

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Identifiers

PMID: 31892165
DOI: 10.3390/ijms21010197
PMCID: PMC6982016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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