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Article

Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease.

Physiological reports - 1 Jun 2017

Cutler Tamara S, Park Saemi, Loh Dawn H, Jordan Maria C, Yokota Tomohiro, Roos Kenneth P, Ghiani Cristina A, Colwell Christopher S

Abstract excerpt

Cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with Huntington's disease (HD). Preclinical research requires mouse models that recapitulate disease symptoms and the Q175 knock-in model offers a number of advantages but potential autonomic dysfunction has not been explored. In this study, we sought to test...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28576852
DOI: 10.14814/phy2.13289
PMCID: PMC5471434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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