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Article

Polymorphisms of the Bcl-2 family member bfl-1 in children with atopic dermatitis.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Dec 2006

Gray Andrew, Stewart Helen, Pravica Vera, Fryer Anthony A, Lenney Warren, Hutchinson Ian V, Arkwright Peter D

Abstract excerpt

T lymphocytes accumulating in the skin of patients with atopic dermatitis (AD) have a prolonged survival and are key mediators of this inflammatory disease. The anti-apoptotic bfl-1 gene is unique in that it is the only member of the Bcl-2 family that is transcriptionally regulated by inflammatory cytokines and might therefore be important in promoting the survival of effector T cells in patients with AD. The aim...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-bcl-2

Source

Identifiers

PMID: 17121585
DOI: 10.1111/j.1399-3038.2006.00468.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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