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Evaluation of polymorphic variants in apoptotic genes (Bcl-2 / Bax) and their roles in the development of myeloproliferative disorders (hematological malignancies) a case-controlled study.

2022-02-28

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<title>Abstract</title> <p><bold>Background:</bold>BCL2 and Bax play important roles in the regulation of apoptosis. The Bax-G(-248)A AND Bcl-2-938C>A polymorphisms in the promoter region were associated with low Bax expression, and high Bcl-2 expression, respectively. These likely affect on hematological malignancies on different parameters such as advanced stage, treatment resistance, and short overall survival...

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Literature Corpus work: 9912b6c6-a266-51a9-94c2-a78980d87936
DOI: 10.21203/rs.3.rs-1386196/v1

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