Article
A Study Investigating the Role of 2 Candidate SNPs in Bax and Bcl-2 Genes in Alzheimer's Disease.
Puerto Rico health sciences journal - 1 Sept 2020
Erdal Mehmet Emin, Görücü Yilmaz Senay, Ay Mustafa Ertan, Güler Kara Hale, Avci Özge Aynur, Tasdelen Bahar
Abstract excerpt
OBJECTIVE: The proto-oncogene Bax (Bcl-2-associated X protein) and related protein Bcl-2 (B-cell chronic lymphocytic leukemia/lymphoma-2) genes are triggers of apoptosis in Alzheimer's disease (AD). The balance of these proteins has an important role in the death or life of a neuronal cell, and the functional polymorphisms in genes expressing these proteins have been found to promote apoptosis. To investigate the...
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