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Article

Identification of a Human SOCS1 Polymorphism That Predicts Rheumatoid Arthritis Severity.

Frontiers in immunology - 1 Jan 2020

Lamana Amalia, Villares Ricardo, Seoane Iria V, Andrés Nuria, Lucas Pilar, Emery Paul, Vital Edward M, Triguero-Martínez Ana, Marquez Ana, Ortiz Ana M, Maxime Robin, Martínez Carmen, Martín Javier, Gomariz Rosa P, Ponchel Frederique, González-Álvaro Isidoro, Mellado Mario

Abstract excerpt

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by an autoimmune response in the joints and an exacerbation of cytokine responses. A minority of patients with RA experience spontaneous remission, but most will show moderate/high disease activity, with aggressive joint damage and multiple systemic manifestations. There is thus is a great need to identify prognostic biomarkers for disease...

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Identifiers

PMID: 32670294
DOI: 10.3389/fimmu.2020.01336
PMCID: PMC7332777

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