Article
Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population.
Journal of human genetics - 1 Jan 2007
Chae Soo-Cheon, Li Chun-Shi, Kim Ki Mo, Yang Ji Yeon, Zhang Qinggao, Lee Yong-Chul, Yang Yun-Sik, Chung Hun-Taeg
Abstract excerpt
Interleukin 27 (IL-27) acts as a versatile cytokine in the early regulation of Th1 initiation and in the negative regulation of the Th2 factor GATA-3. IL-27, which was discovered as a novel heterodimeric cytokine of the IL-12 family, consists of two subunits, the Epstein-Barr virus-induced gene 3...
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