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Article

Single nucleotide polymorphisms in collagenous lectins and other innate immune genes in pigs with common infectious diseases.

Veterinary immunology and immunopathology - 15 Jul 2011

Keirstead N D, Hayes M A, Vandervoort G E, Brooks A S, Squires E J, Lillie B N

Abstract excerpt

Innate immune recognition of pathogens involves various surface receptors and soluble proteins that precede agglutination, complement activation, phagocytosis, and the adaptive immune response. Mannan-binding lectins (MBLs), ficolins (FCNs) and surfactant protein A (SP-A) are soluble collagenous lectins that bind surface structures of various bacteria, viruses and fungi. Some single nucleotide polymorphisms...

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PMID: 21570129
DOI: 10.1016/j.vetimm.2011.02.011

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