Article
Single nucleotide polymorphisms in mannan-binding lectins and ficolins in various strains of mice.
International journal of immunogenetics - 1 Aug 2007
Phaneuf L R, Lillie B N, Hayes M A, Turner P V
Abstract excerpt
Mannan-binding lectin (MBL) and ficolin are collagenous lectins produced primarily by the liver and are involved in innate resistance to microbial pathogens. Mice have two MBL genes (Mbl1 and Mbl2) that encode MBL-A and MBL-C, respectively. Similarly, the murine Fcna and Fcnb genes encode ficolin-A and ficolin-B. Several single nucleotide polymorphisms (SNP) in the human MBL2 gene are responsible for various...
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