Polymorphisms in mannose-binding lectin (MBL) gene and their association with MBL protein levels in serum in the Hu sheep.

doi:10.1016/j.vetimm.2010.12.009

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Polymorphisms in mannose-binding lectin (MBL) gene and their association with MBL protein levels in serum in the Hu sheep.

Veterinary immunology and immunopathology - 15 Apr 2011

Zhao Feng, Zhao Zongsheng, Yan Genqiang, Wang Dong, Ban Qian, Yu Peng, Zhang Wenxiang, Luo Yan

Abstract excerpt

Mannose-binding lectin (MBL) is the archetypical pathogen recognition protein of the innate immune defence. In humans, three frequently occurring single nucleotide polymorphisms (SNPs) in the coding region of MBL gene are associated with the abnormal polymerization, decreased serum concentration and strongly impaired function of MBL protein. To understand whether or not SNPs in MBL gene are associated with serum...

Topics

Amino Acid Sequence
Amino Acid Substitution
Animals
Base Sequence
DNA Primers
Immunity, Innate
Mannose-Binding Lectin
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Polymorphism, Single-Stranded Conformational

Sequence Deletion

Sequence Homology, Amino Acid

Sequence Homology, Nucleic Acid

Sheep

Source

Open in PubMed

Identifiers

PMID: 21333363
DOI: 10.1016/j.vetimm.2010.12.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in mannose-binding lectin (MBL) gene and their association with MBL protein levels in serum in the Hu sheep.PMID 21333363Read ↗

Chicken mannose-binding lectin (MBL) gene variants with influence on MBL serum concentrations.Semantic proximity Read ↗

Polymorphisms and serum level of mannose-binding lectin: an Iranian survey.Semantic proximity Read ↗

Mannose-binding lectin and its genetic variants.Semantic proximity Read ↗

Mannose-binding lectin genetics: from A to Z.Semantic proximity Read ↗

Mannan-binding lectin deficiency - Good news, bad news, doesn't matter?Semantic proximity Read ↗

Mannose-binding lectin deficiency--revisited.Semantic proximity Read ↗

Mannose-binding lectin gene sequence data in Kelantan population.Semantic proximity Read ↗

Mannose-binding lectin (MBL) deficiency. Variant alleles in a midwestern population of the United States.Semantic proximity Read ↗

Mannose-binding lectin: structure, function, genetics and disease associations.Semantic proximity Read ↗

Mannose-binding lectin 1 haplotypes influence serum MBL-A concentration, complement activity, and milk production traits in Chinese Holstein cattle.Semantic proximity Read ↗

Biochemistry and genetics of mannan-binding lectin (MBL)Semantic proximity Read ↗

Characterization of mannose-binding lectin (MBL) variants by allele-specific sequencing of MBL2 and determination of serum MBL protein levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.