Article
[Phenotypic manifestation of epigenetic determinant [ISP+] in Saccharomyces serevisiae depends on combination of mutations in SUP35 and SUP45 genes].
Molekuliarnaia biologiia - 1 Jan 2000
Aksenova A Iu, Volkov K V, Rovinskiĭ N S, Svitin A V, Mironova L N
Abstract excerpt
It is known that translation fidelity in Saccharomyces yeast is determined by factors of genetic and epigenetic (prion) nature. The work represents results of further analysis of strains containing non-chromosomal determinant [ISP+], described earlier. This determinant is involved in the control of translation fidelity and some of its properties indicate that it is a prion. [ISP+] manifests phenotypically as...
Topics
- Chromosomes, Fungal
- Epigenesis, Genetic
- Guanidine
- Mutation
- Peptide Termination Factors
- Phenotype
- Prions
- Protein Biosynthesis
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
